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Latest Discovery
Igniting Momentum: GCT Industry Rekindles in 2023, Poised for Success
Jul 28, 2023
According to the latest quarterly report from ASGCT (American Society of Gene & Cell Therapy) , Q2 2023 proved to be a notable quarter in the field of therapy approvals, with the introduction of six new therapies that garnered regulatory clearance. Read More >
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Research Trend
LARP7-Mediated U6 snRNA Modification and Its Role in Pre-mRNA Splicing As Well As Its Functions in Mouse Spermatogenesis
May 11, 2021
In higher eukaryotes, most genes co Read More >
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Research Trend
Novel Mouse Model for Researching RAB7A and NF-kB Activation
Jan 12, 2021
A recent study has suggested that that NF-kB activation is boosted by colocalization of engaged immune receptors (i.e., CD40) with RAB7 small GTPase on mature endosomes in mouse B cells. This research was enabled by using a conditional (floxed) gene knockin mouse model - Cd19+/creRosa26+/fl-STOP-fl-Rab7 (Rab7 B-Tg) – which is designed to express untagged RAB7 in CD19+ B cells. Read More >
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Latest Discovery
RALY Gene Feature: New Implications in Metabolism and Cholesterogenesis
Aug 18, 2020
The heterogenous nuclear ribonucleoprotein (hnRNP) family are multifunctional complexes of RNA and protein present in the cell nucleus that serve critical roles in gene regulation. Multiple lines of evidence have linked hnRNP abnormalities as key pathobiological drivers of cancer and neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Read More >
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Latest Discovery
Applications of Rat Models in Alzheimer's Disease Discovery Research
Jul 14, 2020
The predominant animal models currently used in the research of Alzheimer's disease (AD) are genetically modified mice. Although promising results have been achieved in this field, almost all corresponding clinical trials have failed, especially with regards to drug development centered on the amyloid hypothesis. Read More >
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Latest Discovery
COVID-19
Factors Contributing to the Age and Sex-Based Differences of the Novel Coronavirus - SARS-CoV-2/COVID-19
Jun 16, 2020
With the growing amount of coronavirus research accomplished by researchers globally, the value of the novel coronavirus (SARS-CoV-2) across many relevant research fields has been confirmed. According to big data analytics, the degree of coronavirus infection varies among different genders and different age groups. Read More >
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Latest Discovery
COVID-19
Differences in COVID-19 Severity Across Patient Populations - Age and Gender
Jun 12, 2020
With the growing amount of coronavirus research accomplished by researchers globally, the value of the novel coronavirus (SARS-CoV-2) across many relevant research fields has been confirmed. According to big data analytics, the degree of coronavirus infection varies among different genders and different age groups. Read More >
Research Trend
Latest Discovery
The Latest Animal Models of Chronic Pancreatitis
May 28, 2020
While chronic pancreatitis (CP) is a relatively common disease, it remains difficult to treat. This is defined as a continuous or recurrent inflammatory pancreatic disease characterized by progressive and irreversible changes in pancreatic morphology. So far, scholars around the globe have done a lot of research on the diagnosis, treatment, and pathogenesis of the disease. Read More >
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Latest Discovery
COVID-19
Understanding SARS-CoV-2: From the Origin to Current Research
May 13, 2020
The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become an ongoing global health emergency. Herein, we track the virus from its origin to current research efforts, with the aim of providing inspiration for further research and vaccine development. Read More >
Latest Discovery
Advancing the Study of Cardiac Chamber Specification During Development & Pathological Remodeling
Aug 06, 2019
Nppa (natriuretic peptide A) is a cardiac hormone that dynamically changes its spatiotemporal expression during heart development. Read More >